Enhancing Akt Imaging through Targeted Reporter Expression

The serine/threonine kinase PKB/Akt is a key mediator of survival and resistance to cancer therapy. Pharmacologic inhibition of Akt and its biologic sequelae may significantly impact the treatment of cancer. The use of molecular imaging technologies has contributed significantly to drug discovery re...

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Bibliographic Details
Main Authors: Limin Zhang, Mahaveer S. Bhojani, Brian D. Ross, Alnawaz Rehemtulla
Format: Article
Language:English
Published: SAGE Publications 2008-07-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2008.00017A