Review: Role of metformin in the management of polycystic ovary syndrome
Polycystic ovary syndrome is the most common endocrinological disorder affecting 4-12% of women and also the most controversial. Metformin was logically introduced to establish the extent to which hyperinsulinaemia influences the pathogenesis of the condition. Early studies were very encouraging. Ra...
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Format: | Article |
Language: | English |
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SAGE Publishing
2010-08-01
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Series: | Therapeutic Advances in Endocrinology and Metabolism |
Online Access: | https://doi.org/10.1177/2042018810380215 |
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author | Hany Lashen |
author_facet | Hany Lashen |
author_sort | Hany Lashen |
collection | DOAJ |
description | Polycystic ovary syndrome is the most common endocrinological disorder affecting 4-12% of women and also the most controversial. Metformin was logically introduced to establish the extent to which hyperinsulinaemia influences the pathogenesis of the condition. Early studies were very encouraging. Randomized controlled studies and several meta-analyses have changed the picture and put the drug that was once heralded as magic in a much contracted place. More work is needed to establish its right place in particular with regards to the prevention of many gestational and long-term complications. |
first_indexed | 2024-12-19T15:50:15Z |
format | Article |
id | doaj.art-8ff5b09561e14160996fea790d7c328a |
institution | Directory Open Access Journal |
issn | 2042-0188 |
language | English |
last_indexed | 2024-12-19T15:50:15Z |
publishDate | 2010-08-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Therapeutic Advances in Endocrinology and Metabolism |
spelling | doaj.art-8ff5b09561e14160996fea790d7c328a2022-12-21T20:15:13ZengSAGE PublishingTherapeutic Advances in Endocrinology and Metabolism2042-01882010-08-01110.1177/2042018810380215Review: Role of metformin in the management of polycystic ovary syndromeHany LashenPolycystic ovary syndrome is the most common endocrinological disorder affecting 4-12% of women and also the most controversial. Metformin was logically introduced to establish the extent to which hyperinsulinaemia influences the pathogenesis of the condition. Early studies were very encouraging. Randomized controlled studies and several meta-analyses have changed the picture and put the drug that was once heralded as magic in a much contracted place. More work is needed to establish its right place in particular with regards to the prevention of many gestational and long-term complications.https://doi.org/10.1177/2042018810380215 |
spellingShingle | Hany Lashen Review: Role of metformin in the management of polycystic ovary syndrome Therapeutic Advances in Endocrinology and Metabolism |
title | Review: Role of metformin in the management of polycystic ovary syndrome |
title_full | Review: Role of metformin in the management of polycystic ovary syndrome |
title_fullStr | Review: Role of metformin in the management of polycystic ovary syndrome |
title_full_unstemmed | Review: Role of metformin in the management of polycystic ovary syndrome |
title_short | Review: Role of metformin in the management of polycystic ovary syndrome |
title_sort | review role of metformin in the management of polycystic ovary syndrome |
url | https://doi.org/10.1177/2042018810380215 |
work_keys_str_mv | AT hanylashen reviewroleofmetformininthemanagementofpolycysticovarysyndrome |