Review: Role of metformin in the management of polycystic ovary syndrome

Polycystic ovary syndrome is the most common endocrinological disorder affecting 4-12% of women and also the most controversial. Metformin was logically introduced to establish the extent to which hyperinsulinaemia influences the pathogenesis of the condition. Early studies were very encouraging. Ra...

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Main Author: Hany Lashen
Format: Article
Language:English
Published: SAGE Publishing 2010-08-01
Series:Therapeutic Advances in Endocrinology and Metabolism
Online Access:https://doi.org/10.1177/2042018810380215
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author Hany Lashen
author_facet Hany Lashen
author_sort Hany Lashen
collection DOAJ
description Polycystic ovary syndrome is the most common endocrinological disorder affecting 4-12% of women and also the most controversial. Metformin was logically introduced to establish the extent to which hyperinsulinaemia influences the pathogenesis of the condition. Early studies were very encouraging. Randomized controlled studies and several meta-analyses have changed the picture and put the drug that was once heralded as magic in a much contracted place. More work is needed to establish its right place in particular with regards to the prevention of many gestational and long-term complications.
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spelling doaj.art-8ff5b09561e14160996fea790d7c328a2022-12-21T20:15:13ZengSAGE PublishingTherapeutic Advances in Endocrinology and Metabolism2042-01882010-08-01110.1177/2042018810380215Review: Role of metformin in the management of polycystic ovary syndromeHany LashenPolycystic ovary syndrome is the most common endocrinological disorder affecting 4-12% of women and also the most controversial. Metformin was logically introduced to establish the extent to which hyperinsulinaemia influences the pathogenesis of the condition. Early studies were very encouraging. Randomized controlled studies and several meta-analyses have changed the picture and put the drug that was once heralded as magic in a much contracted place. More work is needed to establish its right place in particular with regards to the prevention of many gestational and long-term complications.https://doi.org/10.1177/2042018810380215
spellingShingle Hany Lashen
Review: Role of metformin in the management of polycystic ovary syndrome
Therapeutic Advances in Endocrinology and Metabolism
title Review: Role of metformin in the management of polycystic ovary syndrome
title_full Review: Role of metformin in the management of polycystic ovary syndrome
title_fullStr Review: Role of metformin in the management of polycystic ovary syndrome
title_full_unstemmed Review: Role of metformin in the management of polycystic ovary syndrome
title_short Review: Role of metformin in the management of polycystic ovary syndrome
title_sort review role of metformin in the management of polycystic ovary syndrome
url https://doi.org/10.1177/2042018810380215
work_keys_str_mv AT hanylashen reviewroleofmetformininthemanagementofpolycysticovarysyndrome