Hyperglycemia Suppresses Calcium Phosphate–Induced Aneurysm Formation Through Inhibition of Macrophage Activation

Hyperglycemia Suppresses Calcium Phosphate–Induced Aneurysm Formation Through Inhibition of Macrophage Activation

BackgroundThe aim of this study was to elucidate aspects of diabetes mellitus–induced suppression of aneurysm. We hypothesized that high glucose suppresses aneurysm by inhibiting macrophage activation via activation of Nr1h2 (also known as liver X receptor β), recently characterized as a glucose‐sen...

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Bibliographic Details
Main Authors: Teruyoshi Tanaka, Yuichiro Takei, Dai Yamanouchi
Format: Article
Language:English
Published: Wiley 2016-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aneurysm
diabetes mellitus
LXRβ
macrophage activation
metalloproteinases
Nr1h2
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.115.003062

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.115.003062

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