Lifespan extension by preserving proliferative homeostasis in Drosophila.

Regenerative processes are critical to maintain tissue homeostasis in high-turnover tissues. At the same time, proliferation of stem and progenitor cells has to be carefully controlled to prevent hyper-proliferative diseases. Mechanisms that ensure this balance, thus promoting proliferative homeosta...

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Bibliographic Details
Main Authors: Benoît Biteau, Jason Karpac, Stephen Supoyo, Matthew Degennaro, Ruth Lehmann, Heinrich Jasper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2954830?pdf=render