Tau deficiency inhibits classically activated macrophage polarization and protects against collagen-induced arthritis in mice
Abstract Background Tau protein serves a pro-inflammatory function in neuroinflammation. However, the role of tau in other inflammatory disorders such as rheumatoid arthritis (RA) is less explored. This study is to investigate the role of endogenous tau and the potential mechanisms in the pathogenes...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-08-01
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Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13075-023-03133-4 |