Tau deficiency inhibits classically activated macrophage polarization and protects against collagen-induced arthritis in mice

Abstract Background Tau protein serves a pro-inflammatory function in neuroinflammation. However, the role of tau in other inflammatory disorders such as rheumatoid arthritis (RA) is less explored. This study is to investigate the role of endogenous tau and the potential mechanisms in the pathogenes...

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Bibliographic Details
Main Authors: Meng Chen, Wenyu Fu, Huiyun Xu, Chuan-ju Liu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13075-023-03133-4