Amyloid Precursor Protein (APP) Regulates Gliogenesis and Neurogenesis of Human Neural Stem Cells by Several Signaling Pathways

Amyloid Precursor Protein (APP) Regulates Gliogenesis and Neurogenesis of Human Neural Stem Cells by Several Signaling Pathways

Numerous studies have focused on the pathophysiological role of amyloid precursor protein (APP) because the proteolytic processing of APP to β-amyloid (Aβ) peptide is a central event in Alzheimer’s disease (AD). However, many authors consider that alterations in the physiological functions of APP ar...

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Bibliographic Details
Main Authors: Raquel Coronel, Adela Bernabeu-Zornoza, Charlotte Palmer, Rosa González-Sastre, Andreea Rosca, Patricia Mateos-Martínez, Victoria López-Alonso, Isabel Liste
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
amyloid precursor protein
neural stem cells
neurogenesis
gliogenesis
signaling pathways
RNA sequencing
Online Access:https://www.mdpi.com/1422-0067/24/16/12964

Internet

https://www.mdpi.com/1422-0067/24/16/12964

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