Genomic Profiling of Sarcomas: A Promising Weapon in the Therapeutic Arsenal

Genomic Profiling of Sarcomas: A Promising Weapon in the Therapeutic Arsenal

Sarcomas are rare malignant mesenchymal neoplasms, and the knowledge of tumor biology and genomics is scarce. Chemotherapy is the standard of care in advanced disease, with poor outcomes. Identifying actionable genomic alterations may offer effective salvage therapeutic options when previous lines h...

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Bibliographic Details
Main Authors: Raquel Lopes-Brás, Dolores Lopez-Presa, Miguel Esperança-Martins, Cecília Melo-Alvim, Lina Gallego, Luís Costa, Isabel Fernandes
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
cancer care
comprehensive genomic profiling
genomics
next-generation sequencing
rare tumor
sarcoma sequencing-directed therapy
Online Access:https://www.mdpi.com/1422-0067/23/22/14227

Internet

https://www.mdpi.com/1422-0067/23/22/14227

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