Effect of microserum environment stimulation on extraction and biological function of colorectal cancer stem cells

Abstract Background 3D cancer stem cell (CSC) cultures are widely used as in vitro tumor models. In this study, we determined the effects of enriching HCT116 tumor spheres initially cultured in serum-free medium with different concentrations of serum, focusing on the effect of microserum environment...

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Bibliographic Details
Main Authors: Feiqing Wang, Jianing Zhao, Chike Zhang, Bo Yang, Tingting Tian, Mengxian Tian, Na Meng, Wei Xie, Guangyang Liu, Xiaodong Zhu, Min Su, Zhixu He, Yang Liu, Dongxin Tang, Yanju Li
Format: Article
Language:English
Published: Springer 2023-08-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00779-z