Carboplatin Dosing in Children Using Estimated Glomerular Filtration Rate: Equation Matters

Carboplatin Dosing in Children Using Estimated Glomerular Filtration Rate: Equation Matters

Renal function-based carboplatin dosing using measured glomerular filtration rate (GFR) results in more consistent drug exposure than anthropometric dosing. We aimed to validate the Newell dosing equation using estimated GFR (eGFR) and study which equation most accurately predicts carboplatin cleara...

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Bibliographic Details
Main Authors: Mirjam E. van de Velde, Emil den Bakker, Hester N. Blufpand, Gertjan L. Kaspers, Floor C. H. Abbink, Arjenne W. A. Kors, Abraham J. Wilhelm, Richard J. Honeywell, Godefridus J. Peters, Birgit Stoffel-Wagner, Laurien M. Buffart, Arend Bökenkamp
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
carboplatin
children
renal function-based dosing
glomerular filtration rate
cystatin C
retinoblastoma
Online Access:https://www.mdpi.com/2072-6694/13/23/5963

Internet

https://www.mdpi.com/2072-6694/13/23/5963

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