A high-throughput screen identifying sequence and promiscuity characteristics of the <it>loxP </it>spacer region in Cre-mediated recombination

<p>Abstract</p> <p>Background</p> <p>Cre-<it>loxP </it>recombination refers to the process of site-specific recombination mediated by two <it>loxP </it>sequences and the Cre recombinase protein. Transgenic experiments exploit integrative recombin...

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Bibliographic Details
Main Authors: Holt Robert A, Smailus Duane E, Missirlis Perseus I
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/7/73