Tofacitinib Reduces Spinal Inflammation in Vertebral Bodies and Posterolateral Elements in Ankylosing Spondylitis: Results from a Phase 2 Trial

Tofacitinib Reduces Spinal Inflammation in Vertebral Bodies and Posterolateral Elements in Ankylosing Spondylitis: Results from a Phase 2 Trial

Abstract Introduction This post hoc analysis of phase 2 trial data assessed the efficacy of tofacitinib on magnetic resonance imaging (MRI) outcomes with the detailed anatomy-based Canada–Denmark (CANDEN) MRI scoring system and evaluated tofacitinib suppression of spinal inflammation in patients wit...

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Bibliographic Details
Main Authors: Mikkel Østergaard, Joseph Wu, Lara Fallon, Sarah P. Sherlock, Cunshan Wang, Dona Fleishaker, Keith S. Kanik, Walter P. Maksymowych
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-06-01
Series:Rheumatology and Therapy
Subjects:
Ankylosing spondylitis
Clinical trial
Magnetic resonance imaging
Online Access:https://doi.org/10.1007/s40744-023-00564-y

Internet

https://doi.org/10.1007/s40744-023-00564-y

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