PLGA-PEG-PLGA hydrogel with NEP1-40 promotes the functional recovery of brachial plexus root avulsion in adult rats

Adult brachial plexus root avulsion can cause serious damage to nerve tissue and impair axonal regeneration, making the recovery of nerve function difficult. Nogo-A extracellular peptide residues 1-40 (NEP1-40) promote axonal regeneration by inhibiting the Nogo-66 receptor (NgR1), and poly (D, L-lac...

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Bibliographic Details
Main Authors: Wenlai Guo, Bingbing Pei, Zehui Li, Xiao Lan Ou, Tianwen Sun, Zhe Zhu
Format: Article
Language:English
Published: PeerJ Inc. 2021-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12269.pdf