Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling

Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling

Angiogenesis is critical for tissue repair following myocardial infarction (MI), which is exacerbated under insulin resistance or diabetes. MicroRNAs are regulators of angiogenesis. We examined the metabolic regulation of miR-409-3p in post-infarct angiogenesis. miR-409-3p was increased in patients...

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Bibliographic Details
Main Authors: Furkan Bestepe, Colette Fritsche, Kartik Lakhotiya, Carolyn E. Niosi, George F. Ghanem, Gregory L. Martin, Ruma Pal-Ghosh, Dakota Becker-Greene, James Weston, Ivana Hollan, Ivar Risnes, Stein Erik Rynning, Liv Heidi Solheim, Mark W. Feinberg, Robert M. Blanton, Basak Icli
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Non-coding RNAs
angiogenesis
endothelial cells
microRNAs
acute myocardial infarction
DNAJB9
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123001385

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http://www.sciencedirect.com/science/article/pii/S2162253123001385

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