Human ADSC xenograft through IL-6 secretion activates M2 macrophages responsible for the repair of damaged muscle tissue

Human ADSC xenograft through IL-6 secretion activates M2 macrophages responsible for the repair of damaged muscle tissue

Abstract Background Adipose-derived mesenchymal stromal cells (ADSCs) are multipotent stromal cells. The cells secrete a number of cytokines and growth factors and show immunoregulatory and proangiogenic properties. Their properties may be used to repair damaged tissues. The aim of our work is to ex...

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Bibliographic Details
Main Authors: Ewelina Pilny, Ryszard Smolarczyk, Magdalena Jarosz-Biej, Alina Hadyk, Agnieszka Skorupa, Mateusz Ciszek, Łukasz Krakowczyk, Natalia Kułach, Danuta Gillner, Maria Sokół, Stanisław Szala, Tomasz Cichoń
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Stem Cell Research & Therapy
Subjects:
hADSCs
IL-6
M2 macrophages
Blood vessels
Repairing damaged muscle
Xenograft
Online Access:http://link.springer.com/article/10.1186/s13287-019-1188-y

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http://link.springer.com/article/10.1186/s13287-019-1188-y

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