TREM2 Is Associated with Advanced Stages and Inferior Prognosis in Oral Squamous Cell Carcinoma

TREM2 Is Associated with Advanced Stages and Inferior Prognosis in Oral Squamous Cell Carcinoma

Triggering receptor expressed on myeloid cells 2 (TREM2) is suggested to hamper antitumor immune response in multiple cancers. However, the role of TREM2 in oral squamous cell carcinoma (OSCC) and its expression in tumor-associated macrophages (TAMs) are unknown. In this study, TREM2 expression was...

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Bibliographic Details
Main Authors: Ann-Kristin Struckmeier, Anne Radermacher, Michael Fehrenz, Dalia Alansary, Philipp Wartenberg, Mathias Wagner, Anja Scheller, Jochen Hess, Julius Moratin, Christian Freudlsperger, Jürgen Hoffmann, Lorenz Thurner, Klaus Roemer, Kolja Freier, Dominik Horn
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
TREM2
oral squamous cell carcinoma (OSCC)
tumor-associated macrophages (TAMs)
tumor microenvironment (TME)
sTREM2
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/14/19/4635

Internet

https://www.mdpi.com/2072-6694/14/19/4635

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