WDPCP Modulates Cilia Beating Through the MAPK/ERK Pathway in Chronic Rhinosinusitis With Nasal Polyps

WDPCP Modulates Cilia Beating Through the MAPK/ERK Pathway in Chronic Rhinosinusitis With Nasal Polyps

Cilia loss and dysfunction is one of the typical pathological features of chronic rhinosinusitis with nasal polyps (CRSwNP). Tryptophan-aspartic acid (W-D) repeat containing planar cell polarity effector (WDPCP) has been proven to be an essential element for ciliogenesis in human nasal epithelium, b...

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Bibliographic Details
Main Authors: Yun Ma, Peng Tian, Hua Zhong, Fan Wu, Qining Zhang, Xiang Liu, Hua Dang, Qiujian Chen, Hua Zou, Yiqing Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
WDPCP
cilia beating
mitochondria
MAPK/ERK pathway
chronic rhinosinusitis with nasal polyps (CRSwNP)
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.630340/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.630340/full

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