Restriction site associated DNA sequencing for tumour mutation burden estimation and mutation signature analysis
Abstract Background Genome‐wide measures of genetic disruption such as tumour mutation burden (TMB) and mutation signatures are emerging as useful biomarkers to stratify patients for treatment. Clinicians commonly use cancer gene panels for tumour mutation burden estimation, and whole genome sequenc...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-12-01
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Series: | Cancer Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/cam4.6711 |