Progressive Cardiac Metabolic Defects Accompany Diastolic and Severe Systolic Dysfunction in Spontaneously Hypertensive Rat Hearts

Progressive Cardiac Metabolic Defects Accompany Diastolic and Severe Systolic Dysfunction in Spontaneously Hypertensive Rat Hearts

Background Cardiac metabolic abnormalities are present in heart failure. Few studies have followed metabolic changes accompanying diastolic and systolic heart failure in the same model. We examined metabolic changes during the development of diastolic and severe systolic dysfunction in spontaneously...

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Bibliographic Details
Main Authors: Jie Li, Krzysztof Minczuk, Qiao Huang, Brandon A. Kemp, Nancy L. Howell, Mahendra D. Chordia, R. Jack Roy, James T. Patrie, Zoraiz Qureshi, Christopher M. Kramer, Frederick H. Epstein, Robert M. Carey, Bijoy K. Kundu, Susanna R. Keller
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac magnetic resonance imaging
diastolic and systolic function
dynamic FDG PET
left ventricular hypertrophy
myocardial metabolism
spontaneously hypertensive rats
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.026950

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https://www.ahajournals.org/doi/10.1161/JAHA.122.026950

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