Prenatal administration of multipotent adult progenitor cells modulates the systemic and cerebral immune response in an ovine model of chorioamnionitis

Prenatal administration of multipotent adult progenitor cells modulates the systemic and cerebral immune response in an ovine model of chorioamnionitis

Systemic and cerebral inflammation following antenatal infection (e.g. chorioamnionitis) and dysregulation of the blood brain barrier (BBB) are major risk factors for abnormal neonatal brain development. Administration of multipotent adult progenitor cells (MAPCs) represents an interesting pharmacol...

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Bibliographic Details
Main Authors: Luise Klein, Daan R.M.G. Ophelders, Daniel van den Hove, Maurits Damoiseaux, Bart P.F. Rutten, Chris P.M. Reutelingsperger, Leon J. Schurgers, Tim G.A.M. Wolfs
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Antenatal inflammation
Stem cell therapy
Immunomodulation
Neuro-immune axis
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354622000485

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http://www.sciencedirect.com/science/article/pii/S2666354622000485

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