Δ9-tetrahydrocannabinol prevents methamphetamine-induced neurotoxicity.
Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS), production of peroxynitrites, microglia stimulation, and induces hyperthermia and anorectic effects. Most METH recreational users also consume c...
Main Authors: | M Paola Castelli, Camilla Madeddu, Alberto Casti, Angelo Casu, Paola Casti, Maria Scherma, Liana Fattore, Paola Fadda, M Grazia Ennas |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
Public Library of Science (PLoS)
2014-01-01
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סדרה: | PLoS ONE |
גישה מקוונת: | http://europepmc.org/articles/PMC4028295?pdf=render |
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