Harmonizing across datasets to improve the transferability of drug combination prediction

Abstract Combination treatment has multiple advantages over traditional monotherapy in clinics, thus becoming a target of interest for many high-throughput screening (HTS) studies, which enables the development of machine learning models predicting the response of new drug combinations. However, mos...

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Bibliographic Details
Main Authors: Hanrui Zhang, Ziyan Wang, Yiyang Nan, Bulat Zagidullin, Daiyao Yi, Jing Tang, Yuanfang Guan
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04783-5