The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation.

The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation.

Retinoic acid receptor (RAR) signaling is important for regulating transcriptional activity of genes involved in growth, differentiation, metabolism and reproduction. Defects in RAR signaling have been implicated in cancer. TEL, a member of the ETS family of transcription factors, is a DNA-binding t...

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Bibliographic Details
Main Authors: Magda A Meester-Smoor, Marjolein J F W Janssen, W Martijn ter Haar, Karel H M van Wely, Albert-Jan L H J Aarnoudse, Gertine van Oord, Gabrielle B A van Tilburg, Ellen C Zwarthoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3174942?pdf=render

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http://europepmc.org/articles/PMC3174942?pdf=render

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