Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouse.

The neuroendocrine and metabolic effects of leptin have been extensively researched since the discovery, and the later identification, of the leptin gene mutated within the ob/ob mouse. Leptin is required for optimal health in a number of physiological systems (e.g. fertility, bone density, body wei...

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Bibliographic Details
Main Authors: Deanna Marie Arble, Martha Hotz Vitaterna, Fred W Turek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3176308?pdf=render