HSF4/COIL complex‐dependent R‐loop mediates ultraviolet‐induced inflammatory skin injury

HSF4/COIL complex‐dependent R‐loop mediates ultraviolet‐induced inflammatory skin injury

Abstract Intense ultraviolet (UV) exposure can cause phototoxic reactions, such as skin inflammation, resulting in injury. UV is a direct cause of DNA damage, but the mechanisms underlying transcriptional regulation within cells after DNA damage are unclear. The bioinformatics analysis of transcript...

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Bibliographic Details
Main Authors: Yi‐qian Feng, Heng Zhang, Jing‐xia Han, Bi‐jia Cui, Lu‐ning Qin, Lei Zhang, Qing‐qing Li, Xin‐ying Wu, Nan‐nan Xiao, Yan Zhang, Ting‐ting Lin, Hui‐juan Liu, Tao Sun
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Clinical and Translational Medicine
Subjects:
DNA damage
R‐loop
small‐molecule drugs
transcription factor regulation
UV irradiation
Online Access:https://doi.org/10.1002/ctm2.1336

Internet

https://doi.org/10.1002/ctm2.1336

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