Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1<i>H</i>)-One Scaffold

Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1<i>H</i>)-One Scaffold

A growing body of evidence underlines the crucial role of GPR55 in physiological and pathological conditions. In fact, GPR55 has recently emerged as a therapeutic target for several diseases, including cancer and neurodegenerative and metabolic disorders. Several lines of evidence highlight GPR55′s...

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Bibliográfalaš dieđut
Váldodahkkit: Costanza Ceni, Michael J. Benko, Kawthar A. Mohamed, Giulio Poli, Miriana Di Stefano, Tiziano Tuccinardi, Maria Digiacomo, Massimo Valoti, Robert B. Laprairie, Marco Macchia, Simone Bertini
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: MDPI AG 2022-06-01
Ráidu:Pharmaceuticals
Fáttát:
GPR55
GPR55 agonist
GPR55 modulator
p-ERK activation assay
quinolin-2-one
benzylquinolin-2-one
Liŋkkat:https://www.mdpi.com/1424-8247/15/7/768

Interneahtta

https://www.mdpi.com/1424-8247/15/7/768

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