BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction.

Host cell factors can either positively or negatively regulate the assembly and egress of HIV-1 particles from infected cells. Recent reports have identified a previously uncharacterized transmembrane protein, tetherin/CD317/BST-2, as a crucial host restriction factor that acts during a late budding...

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Bibliographic Details
Main Authors: Kei Miyakawa, Akihide Ryo, Tsutomu Murakami, Kenji Ohba, Shoji Yamaoka, Mitsunori Fukuda, John Guatelli, Naoki Yamamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2788703?pdf=render