BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction.
Host cell factors can either positively or negatively regulate the assembly and egress of HIV-1 particles from infected cells. Recent reports have identified a previously uncharacterized transmembrane protein, tetherin/CD317/BST-2, as a crucial host restriction factor that acts during a late budding...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-12-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2788703?pdf=render |