Clinical and Analytical Validation of a Novel Urine-Based Test for the Detection of Allograft Rejection in Renal Transplant Patients

Clinical and Analytical Validation of a Novel Urine-Based Test for the Detection of Allograft Rejection in Renal Transplant Patients

In this clinical validation study, we developed and validated a urinary Q-Score generated from the quantitative test QSant, formerly known as QiSant, for the detection of biopsy-confirmed acute rejection in kidney transplants. Using a cohort of 223 distinct urine samples collected from three indepen...

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Bibliographic Details
Main Authors: Niamh Nolan, Katherine Valdivieso, Rekha Mani, Joshua Y. C. Yang, Reuben D. Sarwal, Phoebe Katzenbach, Kavita Chalasani, Donna Hongo, Gladys Lugtu, Corinne Mark, Edna Chen, Reggie Nijor, David Savoca, David S. Wexler, Todd Whitson, Shih-Jwo Huang, Lucy H. Lu, Robert J. X. Zawada, Evangelos Hytopoulos, Minnie M. Sarwal
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Journal of Clinical Medicine
Subjects:
acute rejection
subclinical rejection
T cell-mediated rejection
antibody-mediated rejection
cell-free DNA
CXCL10
Online Access:https://www.mdpi.com/2077-0383/9/8/2325

Internet

https://www.mdpi.com/2077-0383/9/8/2325

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