Mechanism of ADP-Inhibited ATP Hydrolysis in Single Proton-Pumping F<sub>o</sub>F<sub>1</sub>-ATP Synthase Trapped in Solution

Mechanism of ADP-Inhibited ATP Hydrolysis in Single Proton-Pumping F<sub>o</sub>F<sub>1</sub>-ATP Synthase Trapped in Solution

F<sub>o</sub>F<sub>1</sub>-ATP synthases in mitochondria, in chloroplasts, and in most bacteria are proton-driven membrane enzymes that supply the cells with ATP made from ADP and phosphate. Different control mechanisms exist to monitor and prevent the enzymes’ reverse chemic...

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Bibliographic Details
Main Authors: Iván Pérez, Thomas Heitkamp, Michael Börsch
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
F<sub>o</sub>F<sub>1</sub>-ATP synthase
ATP hydrolysis
ADP inhibition
single-molecule FRET
ABEL trap
subunit rotation
Online Access:https://www.mdpi.com/1422-0067/24/9/8442

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https://www.mdpi.com/1422-0067/24/9/8442

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