GPCR transactivation signalling in vascular smooth muscle cells: role of NADPH oxidases and reactive oxygen species

The discovery and extension of G-protein-coupled receptor (GPCR) transactivation-dependent signalling has enormously broadened the GPCR signalling paradigm. GPCRs can transactivate protein tyrosine kinase receptors (PTKRs) and serine/threonine kinase receptors (S/TKRs), notably the epidermal growth...

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Bibliographic Details
Main Authors: Raafat Mohamed, Reearna Janke, Wanru Guo, Yingnan Cao, Ying Zhou, Wenhua Zheng, Hossein Babaahmadi-Rezaei, Suowen Xu, Danielle Kamato, Peter J Little
Format: Article
Language:English
Published: Bioscientifica 2019-08-01
Series:Vascular Biology
Subjects:
Online Access:https://vb.bioscientifica.com/view/journals/vb/1/1/VB-18-0004.xml