High Levels of CD244 Rather Than CD160 Associate With CD8+ T-Cell Aging

Aging leads to functional dysregulation of the immune system, especially T cell defects. Previous studies have shown that the accumulation of co-inhibitory molecules plays an essential role in both T cell exhaustion and aging. In the present study, we showed that CD244 and CD160 were both up-regulat...

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Bibliographic Details
Main Authors: Xinyue Wang, Di Wang, Juan Du, Yuqing Wei, Rui Song, Beibei Wang, Shuang Qiu, Bei Li, Leidan Zhang, Yongqin Zeng, Hongxin Zhao, Yaxian Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.853522/full