Eosinophils, but Not Type 2 Innate Lymphoid Cells, Are the Predominant Source of Interleukin 4 during the Innate Phase of <i>Leishmania major</i> Infection

Eosinophils, but Not Type 2 Innate Lymphoid Cells, Are the Predominant Source of Interleukin 4 during the Innate Phase of <i>Leishmania major</i> Infection

Interleukin (IL)-4 plays a central role in the initiation of a type 2 T helper cell (Th2) response, which leads to non-healing and progressive infections with the protozoan parasite <i>Leishmania</i> (<i>L.</i>) <i>major</i>. Here, we tested the hypothesis that ty...

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Bibliographic Details
Main Authors: Carolin Sasse, David Barinberg, Stephanie Obermeyer, Andrea Debus, Ulrike Schleicher, Christian Bogdan
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pathogens
Subjects:
eosinophils
interleukin-4
innate lymphoid cells (ILC)
ILC2
leishmaniasis
<i>Leishmania major</i>
Online Access:https://www.mdpi.com/2076-0817/11/8/828

Internet

https://www.mdpi.com/2076-0817/11/8/828

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