Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues

Robust mapping of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues

Abstract Spatial transcriptomics (ST) technologies generate multiple data types from biological samples, namely gene expression, physical distance between data points, and/or tissue morphology. Here we developed three computational-statistical algorithms that integrate all three data types to advanc...

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Bibliographic Details
Main Authors: Duy Pham, Xiao Tan, Brad Balderson, Jun Xu, Laura F. Grice, Sohye Yoon, Emily F. Willis, Minh Tran, Pui Yeng Lam, Arti Raghubar, Priyakshi Kalita-de Croft, Sunil Lakhani, Jana Vukovic, Marc J. Ruitenberg, Quan H. Nguyen
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43120-6

Internet

https://doi.org/10.1038/s41467-023-43120-6

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