Optimizing the downstream MVA pathway using a combination optimization strategy to increase lycopene yield in Escherichia coli
Abstract Background Lycopene is increasing in demand due to its widespread use in the pharmaceutical and food industries. Metabolic engineering and synthetic biology technologies have been widely used to overexpress the heterologous mevalonate pathway and lycopene pathway in Escherichia coli to prod...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-06-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12934-022-01843-z |