Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunities

Folic Acid Antimetabolites (Antifolates): A Brief Review on Synthetic Strategies and Application Opportunities

Antimetabolites of folic acid represent a large group of drugs and drug candidates, including those for cancer chemotherapy. In this current review, the most common methods and approaches are presented for the synthesis of therapeutically significant antimetabolites of folic acid, which are Methotre...

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Bibliographic Details
Main Authors: Igor S. Kovalev, Grigory V. Zyryanov, Sougata Santra, Adinath Majee, Mikhail V. Varaksin, Valery N. Charushin
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
antifolates
folic acids
synthesis
applications
drugs
Online Access:https://www.mdpi.com/1420-3049/27/19/6229

Internet

https://www.mdpi.com/1420-3049/27/19/6229

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