Síntese e avaliação preliminar da atividade antibacteriana e antifúngica de derivados N-acilidrazônicos

We describe the synthesis and evaluation of N-acylhydrazone compounds bearing different electron-donating groups in one of its aromatic rings, obtained using a four-step synthetic route. IC50 values against pathogenic fungi and bacteria were determined by serial microdilution. Compounds showed low a...

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Bibliographic Details
Main Authors: Thomas Haruo Cachiba, Bruno Demartini Carvalho, Diogo Teixeira Carvalho, Marina Cusinato, Clara Gavião Prado, Amanda Latercia Tranches Dias
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2012-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000800014&lng=en&tlng=en