Cellular response to β‐amyloid neurotoxicity in Alzheimer's disease and implications in new therapeutics

Abstract β‐Amyloid (Aβ) is a specific pathological hallmark of Alzheimer's disease (AD). Because of its neurotoxicity, AD patients exhibit multiple brain dysfunctions. Disease‐modifying therapy (DMT) is the central concept in the development of AD therapeutics today, and most DMT drugs that are...

Full description

Bibliographic Details
Main Authors: Haolin Zhang, Xianghua Li, Xiaoli Wang, Jiayu Xu, Felice Elefant, Juan Wang
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Animal Models and Experimental Medicine
Subjects:
Online Access:https://doi.org/10.1002/ame2.12313