Probing Steroidal Substrate Specificity of Cytochrome P450 BM3 Variants

M01A82W, M11A82W and M01A82WS72I are three cytochrome P450 BM3 (CYP102A1) variants. They can catalyze the hydroxylation of testosterone (TES) and norethisterone at different positions, thereby making them promising biocatalysts for steroid hydroxylation. With the aim of obtaining more hydroxylated s...

Cijeli opis

Bibliografski detalji
Glavni autori: Xing Liu, Zhi-Biao Wang, Ya-Nan Wang, Jian-Qiang Kong
Format: Članak
Jezik:English
Izdano: MDPI AG 2016-06-01
Serija:Molecules
Teme:
Online pristup:http://www.mdpi.com/1420-3049/21/6/760