Aurora kinase a promotes the progression of papillary thyroid carcinoma by activating the mTORC2-AKT signalling pathway

Aurora kinase a promotes the progression of papillary thyroid carcinoma by activating the mTORC2-AKT signalling pathway

Abstract Background Treatment failure is the main cause of death from papillary thyroid carcinoma (PTC). It is urgent to look for new intervention targets and to develop new therapies for treating PTC. Aurora-A kinase (AURKA) functionally regulates cell mitosis and is closely related to the occurren...

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Bibliographic Details
Main Authors: Zewei Zhao, Huijuan Wang, Ning Kang, Zhongyu Wang, Xiukun Hou, Linfei Hu, Shuo Qie, Jianping Guo, Songfeng Wei, Xianhui Ruan, Xiangqian Zheng
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cell & Bioscience
Subjects:
Papillary thyroid carcinoma
AURKA
SIN1
AKT
CUL4B
Online Access:https://doi.org/10.1186/s13578-022-00934-z

Internet

https://doi.org/10.1186/s13578-022-00934-z

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