Preparation and in-vitro characterization of 5-aminosalicylic acid loaded hydrogels for colon specific delivery

Preparation and in-vitro characterization of 5-aminosalicylic acid loaded hydrogels for colon specific delivery

The aim of the current investigation was to prepare and characterize the novel pH-sensitive hydrogels of pluronic F127 and sodium polystyrene sulfonate for the controlled delivery of 5-aminosalicylic acid to colon. Pluronic F127 and sodium polystyrene sulfonate were crosslinked with acrylic acid by...

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Bibliographic Details
Main Authors: Muhammad Suhail, Ming-Chia Hung, I-Hui Chiu, Quoc Lam Vu, Pao-Chu Wu
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Materials Research and Technology
Subjects:
Hydrogel
Sol–gel analysis
Swelling study
In-vivo drug release
HET-CAM test
Online Access:http://www.sciencedirect.com/science/article/pii/S2238785422014387

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http://www.sciencedirect.com/science/article/pii/S2238785422014387

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