Efficient mRNA Delivery with Lyophilized Human Serum Albumin-Based Nanobubbles

Efficient mRNA Delivery with Lyophilized Human Serum Albumin-Based Nanobubbles

In this study, we developed an efficient mRNA delivery vehicle by optimizing a lyophilization method for preserving human serum albumin-based nanobubbles (HSA-NBs), bypassing the need for artificial stabilizers. The morphology of the lyophilized material was verified using scanning electron microsco...

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Bibliographic Details
Main Authors: Hiroshi Kida, Yutaro Yamasaki, Loreto B. Feril Jr., Hitomi Endo, Keiji Itaka, Katsuro Tachibana
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Nanomaterials
Subjects:
nanobubble
lyophilization
sonoporation
mRNA
drug delivery system
ultrasound
Online Access:https://www.mdpi.com/2079-4991/13/7/1283

Internet

https://www.mdpi.com/2079-4991/13/7/1283

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