CD147 receptor is essential for TFF3-mediated signaling regulating colorectal cancer progression

CD147 receptor is essential for TFF3-mediated signaling regulating colorectal cancer progression

Abstract Major gaps in understanding the molecular mechanisms of colorectal cancer (CRC) progression and intestinal mucosal repair have hampered therapeutic development for gastrointestinal disorders. Trefoil factor 3 (TFF3) has been reported to be involved in CRC progression and intestinal mucosal...

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Main Authors: Hong-Yong Cui, Shi-Jie Wang, Fei Song, Xu Cheng, Gang Nan, Yu Zhao, Mei-Rui Qian, Xi Chen, Jia-Yue Li, Fen-Ling Liu, Yu-Meng Zhu, Ruo-Fei Tian, Bin Wang, Bin Wu, Yang Zhang, Xiu-Xuan Sun, Ting Guo, Xiang-Min Yang, Hai Zhang, Ling Li, Jing Xu, Hui-Jie Bian, Jian-Li Jiang, Zhi-Nan Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00677-2

Internet

https://doi.org/10.1038/s41392-021-00677-2

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