Reactive Oxygen and Nitrogen Species in the Development of Pulmonary Hypertension

Reactive Oxygen and Nitrogen Species in the Development of Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is a progressive disease of the lung vasculature that involves the loss of endothelial function together with inappropriate smooth muscle cell growth, inflammation, and fibrosis. These changes underlie a progressive remodeling of blood vessels that alters flow a...

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Bibliographic Details
Main Authors: David J.R. Fulton, Xueyi Li, Zsuzsanna Bordan, Stephen Haigh, Austin Bentley, Feng Chen, Scott A. Barman
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Antioxidants
Subjects:
pulmonary hypertension
reactive oxygen species
nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase)
Nox
nitric oxide
endothelial nitric oxide synthase (eNOS)
Online Access:https://www.mdpi.com/2076-3921/6/3/54

Internet

https://www.mdpi.com/2076-3921/6/3/54

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