Systemic Leptin Produces a Long-Lasting Increase in Respiratory Motor Output in Rats

Systemic Leptin Produces a Long-Lasting Increase in Respiratory Motor Output in Rats

Leptin decreases food intake and increases energy expenditure. Leptin administration into the CNS of mice or rats increases alveolar ventilation and dysfunction in leptin signaling has been implicated in the hypoventilation that can accompany obesity. An increase in CO2 chemosensitivity has been imp...

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Bibliographic Details
Main Authors: Zheng eChang, Edmund eBallou, Weijie eJiao, Kevin E. McKenna, Shaun F. Morrison, Donald R McCrimmon
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Physiology
Subjects:
Leptin
neural control of breathing
Leptin stimulation of breathing
Respiratory plasticity
Metabolic control of breathing
Respiratory modulation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00016/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00016/full

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