Automated estimation of cancer cell deformability with machine learning and acoustic trapping

Abstract Cell deformability is a useful feature for diagnosing various diseases (e.g., the invasiveness of cancer cells). Existing methods commonly inflict pressure on cells and observe changes in cell areas, diameters, or thickness according to the degree of pressure. Then, the Young’s moduli (i.e....

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Bibliographic Details
Main Authors: O-Joun Lee, Hae Gyun Lim, K. Kirk Shung, Jin-Taek Kim, Hyung Ham Kim
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10882-w