Baseline and recurrent exposure to the standard dose of artemisinin-based combination therapies (ACTs) induces oxidative stress and liver damage in mice (BALB/c)

Baseline and recurrent exposure to the standard dose of artemisinin-based combination therapies (ACTs) induces oxidative stress and liver damage in mice (BALB/c)

Abstract Background In malaria-endemic countries, repeated intake of artemisinin-based combination therapies (ACTs) is rampant and driven by drug resistance, improper usage, and easy accessibility. Stress effects and potential liver toxicity due to the frequent therapeutic use of ACTs have not been...

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Bibliographic Details
Main Authors: David Audu, Vinood B. Patel, Olufunmilayo A. Idowu, Fakilahyel M. Mshelbwala, Adewumi B. Idowu
Format: Article
Language:English
Published: SpringerOpen 2023-10-01
Series:Egyptian Liver Journal
Subjects:
Artemether/lumefantrine
Artesunate/amodiaquine
Malondialdehyde
Oxidative stress
Antioxidant
Glutathione peroxidase
Online Access:https://doi.org/10.1186/s43066-023-00291-7

Internet

https://doi.org/10.1186/s43066-023-00291-7

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