The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway

As a ubiquitin sensor and a signal-transducing adaptor, p62 is crucial for NF-κB activation, which involves the ubiquitin machinery in diverse contexts. However, whether p62 is required for EBV LMP1 activation of NF-κB is an open question.

Bibliographic Details
Main Authors: Ling Wang, Mary E. A. Howell, Ayrianna Sparks-Wallace, Juan Zhao, Culton R. Hensley, Camri A. Nicksic, Shanna R. Horne, Kaylea B. Mohr, Jonathan P. Moorman, Zhi Q. Yao, Shunbin Ning
Format: Article
Language:English
Published: American Society for Microbiology 2021-10-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01097-21