Development of Peptide-Based Nanoparticles for Mitochondrial Plasmid DNA Delivery

Development of Peptide-Based Nanoparticles for Mitochondrial Plasmid DNA Delivery

A mitochondrion is a cellular organelle able to produce cellular energy in the form of adenosine triphosphate (ATP). As in the nucleus, mitochondria contain their own genome: the mitochondrial DNA (mtDNA). This genome is particularly susceptible to mutations that are at the basis of a multitude of d...

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Bibliographic Details
Main Authors: Rúben Faria, Eric Vivés, Prisca Boisguerin, Angela Sousa, Diana Costa
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Polymers
Subjects:
biocompatibility
cell-penetrating peptides
mitochondrial DNA diseases
mitochondria targeting
nano-delivery systems
plasmid DNA
Online Access:https://www.mdpi.com/2073-4360/13/11/1836

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https://www.mdpi.com/2073-4360/13/11/1836

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