Pokeweed antiviral protein attenuates liver fibrosis in mice through regulating Wnt/Jnk mediated glucose metabolism

Pokeweed antiviral protein attenuates liver fibrosis in mice through regulating Wnt/Jnk mediated glucose metabolism

Background/Aims: Pokeweed antiviral protein (PAP) has been reported to downregulate Wnt/Jnk pathway and attenuate liver fibrosis. This study was designed to intensively explore the mechanism of anti-fibrosis effect of PAP. Materials and Methods: Hepatic stellate cell (HSC) activation was induced by...

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Bibliographic Details
Main Authors: Yonghong Zhang, Xiaolan Yu, Zheng Wang, Ming Yin, Zonghao Zhao, Yi Li, Wenting Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:The Saudi Journal of Gastroenterology
Subjects:
Glucose metabolism
liver fibrosis
PAP
Wnt/Jnk
Online Access:http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2018;volume=24;issue=3;spage=157;epage=164;aulast=Zhang

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http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2018;volume=24;issue=3;spage=157;epage=164;aulast=Zhang

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