Sophoraflavenone G Restricts Dengue and Zika Virus Infection via RNA Polymerase Interference

Sophoraflavenone G Restricts Dengue and Zika Virus Infection via RNA Polymerase Interference

Flaviviruses including Zika, Dengue and Hepatitis C virus cause debilitating diseases in humans, and the former are emerging as global health concerns with no antiviral treatments. We investigated Sophora Flavecens, used in Chinese medicine, as a source for antiviral compounds. We isolated Sophorafl...

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Bibliographic Details
Main Authors: Alexandre Sze, David Olagnier, Samar Bel Hadj, Xiaoying Han, Xiao Hong Tian, Hong-Tao Xu, Long Yang, Qingwen Shi, Penghua Wang, Mark A. Wainberg, Jian Hui Wu, Rongtuan Lin
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Viruses
Subjects:
flavivirus
Zika virus
Dengue virus
antiviral
therapy
RNA polymerase
Online Access:https://www.mdpi.com/1999-4915/9/10/287

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https://www.mdpi.com/1999-4915/9/10/287

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