Plant TDP1 (Tyrosyl-DNA Phosphodiesterase 1): A Phylogenetic Perspective and Gene Expression Data Mining

Plant TDP1 (Tyrosyl-DNA Phosphodiesterase 1): A Phylogenetic Perspective and Gene Expression Data Mining

The TDP1 (tyrosyl-DNA phosphodiesterase 1) enzyme removes the non-specific covalent intermediates between topoisomerase I and DNA, thus playing a crucial role in preventing DNA damage. While mammals possess only one <i>TDP1</i> gene, in plants two genes (<i>TDP1α</i> and <...

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Bibliographic Details
Main Authors: Giacomo Mutti, Alessandro Raveane, Andrea Pagano, Francesco Bertolini, Ornella Semino, Alma Balestrazzi, Anca Macovei
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
tyrosyl-DNA phosphodiesterase
DNA damage
expression profiling
phylogenetic analysis
sequence organization
Online Access:https://www.mdpi.com/2073-4425/11/12/1465

Internet

https://www.mdpi.com/2073-4425/11/12/1465

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